Cycloferon official instructions for use for children. Auxiliary substances in cycloferon. Is it possible to take Cycloferon for prevention every day

detailed instructions on the use of an antiviral drug with immunostimulating activity - Cycloferon. Doses and treatment regimens for children and adults.

Cycloferon is often prescribed by doctors for the purpose of immunocorrection for preventive and therapeutic purposes in many viral and microbial diseases. We will tell you how to use the medicine correctly in pediatric practice and in adults. Who is contraindicated in treatment with Cycloferon and what complications can be after using the medicine.

Cycloferon: indications for the use of injections, tablets, syrup, nose drops, ointments, suppositories, inhalations

• Cycloferon refers to the pharmacological group of drugs that are interferon inducers. That is, this medicine stimulates the production of its own interferons in the cellular tissues of the intestines, lungs, spleen, and liver.
• In its turn interferons- specific human proteins that protect the body during the invasion of viruses and many pathogens.
• The active ingredient of Cycloferon is the salt of acridoneacetic acid - meglumine acridone acetate.

How Cycloferon works

• The drug effectively suppresses viruses of a diverse nature (various types of influenza, herpes, hepatitis of all types, cytomegalovirus, papillomavirus, human immunodeficiency virus and many others).
• The drug has an antimicrobial effect on many infections (pneumonia, bronchitis, neuroinfections, surgical abscesses, urogenital infections, chlamydia).
• The drug increases the nonspecific resistance (resistance) of the human body to viruses and many microorganisms.
• Cycloferon has an effective interferon-inducing mechanism and promotes the synthesis of interferon in the body.
• Cycloferon is able to relieve pain and inflammatory processes in rheumatic and autoimmune diseases of connective tissues.

• The drug is involved in the formation of the three most important types of immune cells: α-, β-, and γ-interferons.
• Cycloferon is usually prescribed by immunologists in cases of insufficient and weakened own immunity in case of complex viral and microbial intoxications.

IMPORTANT: Cycloferon affects viruses in two ways: the drug stimulates the production of immune cells and blocks the life support of young viral structures.

Cycloferon on the pharmaceutical market is represented by a variety of dosage forms: in the form of tablets of 150 mg, ampoules with a solution (250 mg / 2 ml No. 5) and in the form of 5% liniment (liquid ointment). The products are manufactured by POLYSAN NTFF LLC in the Russian Federation.

IMPORTANT: Cycloferon in the form of syrup, suppositories, drops or nasal spray is not produced in given time. Therefore, if someone offers you medicine in the form of these dosage forms most likely a fake.

Cycloferon solution for intravenous and intramuscular administration 125 mg/ml 2 ml №5

• Injectable Cycloferon is used only as prescribed by a doctor for intramuscular or intravenous administration.
• Parenteral use of the drug is indicated for extensive herpes, meningococcal infection, hepatitis, cytomegalovirus and many severe viral and infectious processes.
• Injections with Cycloferon have a quick effect on the body. The drug quickly enters directly into the blood, bypassing the gastrointestinal tract.
• In broncho-pulmonary diseases, they have indications for inhalation with Cycloferon. The drug combines antiviral and anti-inflammatory properties, so Cycloferon solution copes well with inflammation of the upper respiratory tract.

• Inhalations with Cycloferon are also used for complications after the flu: bronchitis, pneumonia, catarrhal rhinitis, etc.
• For inhalation, a special medical device is used - a nebulizer. Such an inhaler is capable of the smallest dispersion of the drug and its delivery to the smallest alveoli of the lungs.
• A specialized dosage form for inhalation with Cycloferon is not produced, therefore, for these purposes, an injection solution of the drug in ampoules is used.

Cycloferon enteric coated tablets 150mg No. 10, 20 or 50

• For preventive purposes and for the treatment of respiratory organs, Cycloferon is most often used in the form of tablets. The drug enters the bloodstream approximately 30 minutes after ingestion after passing through the entire digestive tract.
• In this case, part of the active component is lost, therefore, the tablet form of Cycloferon has less therapeutic activity compared to the injection.
• To enhance the effect of the tablets and deliver the active ingredient of the drug to the blood as much as possible, the instruction provides for drinking the medicine on an empty stomach or 30 minutes before the start of the meal.
• To reduce drug loss, the tablets are coated with a special enteric coating that prevents the drug from being broken down by gastric juice.
• In this regard, the tablets should be swallowed whole, without chewing and without dividing into separate segments.

Cycloferon liniment 5% bottles 5 ml No. 5 or 30 ml in a tube complete with vaginal applicators

Cycloferon in the form of liquid 5% liniment is intended for external purposes.

• The ointment is applied to blisters of herpes several times a day.
• The drug is prescribed topically, and is also used in the form of urethral and intravaginal instillations for the treatment of urogenital infections of various nature.
• In dentistry, liquid ointment is prescribed for chronic periodontitis.

IMPORTANT: Unlike other immunomodulators, Cycloferon does not contain foreign proteins and is not a drug of modern bioengineering.

As a result, Cycloferon does not have such side effects characteristic of artificial proteins: depression, diarrhea, symptomatic flu-like conditions.

Cycloferon from what age can children?

Instructions for the use of Cycloferon strictly regulate the use of the drug in pediatric practice from the age of 4.

Cycloferon - instructions for use for children and dosage

Cycloferon is prescribed to children according to the instructions and prescription of an immunologist. The algorithm for taking the medicine depends on the age of the child, the nature of the viral or microbial disease, the severity and duration of the disease.

Dosages of Cycloferon tablets for children

• Children from 4 years to 7 years - 1 tablet per day (150 mg).
• Children from 7 years to 11 years old - 2 tablets per day at a time (2x150 mg), 300 mg in total.
• Children aged 12 years and older - 3 tablets per day at a time (3x150 mg), 450 mg in total.

Another course of treatment is possible in 2-3 weeks according to medical indications.

The course of treatment with Cycloferon is prescribed by a doctor

Treatment of herpetic infection, influenza and acute respiratory viral infections, all forms of hepatitis, acute intestinal and HIV infections takes place according to certain and calculated daily basic regimens for taking Cycloferon, which must be strictly adhered to.

How to apply the injection solution of Cycloferon to children?

• Complex viral pathologies require parenteral administration of the drug intramuscularly or intravenously. Cycloferon is administered to children once a day at a dosage of 6-10 mg/kg of the child's body weight.
• Different viral diseases have their own basic prescription regimens that must be strictly observed. The course of treatment in the form of injections is determined by the doctor.

Cycloferon - instructions for use for adults and dosage

Dosages of Cycloferon for adults differ from children's doses

Doses and course of treatment with Cycloferon tablets for adults depend on the diagnosis of a viral infection and the severity of the disease. The drug is prescribed once a day in the required dose.

How to take Cycloferon tablets for adults?

• Intestinal infections - 2 tablets per dose (2x150 mg), total 300 mg.
• Chronic viral hepatitis types B and C, influenza and SARS, neuroinfections, HIV infections, herpes infection - 4 tablets per dose (4x150 mg), 600 mg in total.

At the same time, the basic treatment regimens and the course of taking Cycloferon for each disease are established.

Parenteral use of Cycloferon for adults

• Cycloferon is administered to adults in the form of intramuscular or intravenous injections according to the type of viral infection, the severity of the disease and certain basic regimens.
• Instructions for use recommends parenteral administration of the drug once a day, 250 mg-500 mg, depending on the diagnosis. The course of treatment and the basic scheme of drug administration is determined by the attending physician.

Courses of treatment for parenteral administration of Cycloferon for various diseases

• neuroinfections - 250-500 mg (12 injections)
• herpetic, chlamydial and cytomegalovirus infections 250 mg (10 injections), 2.5 g per course
• acute viral hepatitis A, B, C, D and mixed types - 500 mg (10 injections), 5.0 g per course
• HIV infections - 500 mg (10 injections), 5.0 g per course

How often for a long time to take Cycloferon for prevention for adults and children?

For prophylactic purposes, Cycloferon is prescribed in cases of direct contact of a sick person with healthy people and the risk of intoxication.

The drug is used only when the disease poses a serious threat to human life with weak immunity. Such diseases are:

• viral hepatitis of all varieties
• influenza virus infections
• viral herpes
• cytomegalovirus
• enterovirus
• chlamydial infection
• neuroinfections (meningitis, encephalitis)
• chickenpox in adults

• Cycloferon quickly penetrates into any biological fluids and lingers there. Most of all, the drug is in the lymphoid tissue (up to 72 hours). It is here that the production of its own interferons occurs.
• In the bloodstream, Cycloferon spreads and lingers for a shorter period of time - up to 48 hours.
• Given these factors, the recommended intake of Cycloferon is determined according to the scheme: 1 time in two days. The drug should be taken or injected at the same time to ensure a constant therapeutic amount of the drug in the bloodstream. The success of the cure depends on this.

IMPORTANT: You should strictly adhere to the chosen treatment regimen by an immunologist. The slightest deviations from the chosen standards of treatment can affect the course of the disease in a negative direction.

How often and for how long should Cycloferon be taken for adults and children with colds and flu?

• The effect of Cycloferon on viruses is especially effective in the first hours of intoxication. During this period, the drug almost completely blocks the synthesis of viral DNA.
• The later treatment with Cycloferon is started, the effectiveness of the drug's effect on viruses slows down. We have to fight not only with new viruses, but also to resist the old ones.
• Therefore, with late prescriptions of the drug, treatment may be delayed for an indefinite time.

IMPORTANT: Cycloferon is a powerful antiviral drug that inhibits the reproduction of the virus, especially on early dates diseases (the first 1-2 days).

Scheme of taking Cycloferon for influenza and SARS

• During the treatment of acute respiratory viral infections and instructions for the use of Cycloferon, it recommends a working scheme for taking tablets for adults and children according to the age dosage: on the 1st, 2nd, 4th, 6th and 8th days in the first hours of the disease. The course of treatment is 20 tablets with a dosage of 150 mg.
• AT severe cases influenza virus infection is allowed to take 6 tablets of Cycloferon at once once a day.
• With concomitant high temperature, muscle pain, inflammation of the nasopharynx, complications from the broncho-pulmonary tract, a combination of Cycloferon with other medicines is possible: anti-inflammatory, antipyretic, expectorant, analgesic.

Is it possible to take Cycloferon for prevention every day?

Taking Cycloferon for preventive and therapeutic purposes should be carried out strictly according to the recommended basic medication regimens. It is not recommended to use the drug daily in therapeutic doses. Let's explain why.

• Cycloferon lingers in biological fluids for a certain time and creates the necessary depot of the active substance for a given period of time.
• Lymphoid tissue, which is directed by the action of Cycloferon and where natural interferons are produced, must periodically "rest".
• You should also remove the load from the liver and kidneys, which suffer under the influence of Cycloferon. The drug is independently excreted by the excretory system through the kidneys within 24 hours.

Can Cycloferon be pregnant?

Pregnant women and Cycloferon

Instructions for the use of Cycloferon strictly stipulate that breastfeeding women are not recommended to be treated with the drug due to the toxic effect of the drug on the fetus and children's body.

How to apply Cycloferon at a temperature?

Cycloferon is important to use in the first hours and days from the onset of the disease, even at high temperatures. Moreover, let's say A complex approach in the treatment of influenza with the use of antipyretics at temperatures above 38.5 °.

How to use Cycloferon for chickenpox, herpes?

Cycloferon is a smart medicine

• In nature, 8 types of herpesviruses are known, causing some specific viral infections with characteristic symptoms. Herpes can manifest itself not only in the form of vesicles with liquid contents on the mucous membrane of the lips, eyes, genitals, but also cause a childhood disease such as chickenpox or chicken pox.
• According to WHO, almost all people (90%) are carriers of herpes viruses. When this virus enters the human body, it remains in it forever. When the herpes virus "sleeps", it does not cause a danger to human health, as it is suppressed by our immune system.
• As soon as our immunity fails and weakens, the herpes virus can manifest itself in all its glory and manifest itself in the form of a cold on the mucous membranes.
• To increase the functioning of the immune system and to suppress the virus, doctors prescribe courses of treatment with Cycloferon, using basic regimens for taking the drug.
• Already two hours after the start of treatment with Cycloferon, the patient begins to synthesize his own interferons, which resist a viral infection.
• The basic scheme for taking Cycloferon tablets is given below in dosages appropriate for a given disease and age.

• With chickenpox in adults and herpes of the mucous membranes, Cycloferon is additionally prescribed in the form of 5% liniment for topical use. The ointment is smeared with watery vesicles 2-3 times a day for 5-7 days.
• Due to the structure of the ointment, the active ingredient of the drug quickly penetrates the skin epidermis and effectively begins to work for recovery.

Analogues of Cycloferon

Cycloferon, like its analogues, belongs to interferogens, substances that stimulate the production of natural human body interferons.

Cycloferon is an expensive drug, so sometimes you have to make a choice in the direction of cheaper analogues and drug substitutes. Let's name the most common drugs with antiviral and immunomodulatory activity.

Analogues and substitutes for Cycloferon

Echinacea tincture 25, 40, 50, or 100 ml is the cheapest herbal immunostimulant.

Anaferon lozenges for children and adults - homeopathic remedy activating antiviral immunity.

Amiksin film-coated tablets in a dosage of 60 and 125 mg for children and adults. Contains the active substance - tilorone. Tablets are used as antiviral drug and an inducer of interferon synthesis.

Arbidol film-coated tablets in a dosage of 50 and 100 mg for children and adults with the active substance - umifenovir. Tablets are used as an antiviral and immunostimulating agent.

Galavit in the form of sublingual tablets 25 mg, suppositories and powder 100 mg for solution for injection. The active ingredient of the drug is aminodihydrophthalazinedione sodium. The drug is an immunomodulator and anti-inflammatory drug. Used for treatment viral infections in adults and children over 12 years of age.

Substitutes for Cycloferon

Lavomax film-coated tablets at a dosage of 125 mg with the active substance - tilorone. The drug has an antiviral effect and is also used as a stimulant for the production of interferon. Tablets are prescribed for treatment in adults and adolescents over 18 years of age.

Ingavirin capsules with a dosage of 30, 60 and 90 mg. Contains the active ingredient - imidazolylethanamide pentanedioic acid. It has antiviral efficacy and is also used as an immunostimulating agent in children (from 7 to 17 years old) and in adults.

Oscillococcinum- a French homeopathic preparation used for the prevention and treatment of influenza and acute respiratory viral infections of mild to moderate severity.

Can Cycloferon be taken with antibiotics and combined with alcohol?

Modern standards of treatment suggest, in some cases, the combined use of antibiotics and Cycloferon

• For some bacterial infections, treatment standards prescribe the simultaneous administration of Cycloferon with antibiotics. It should be remembered that such a complex use of drugs should be prescribed by a doctor and not have an independent decision.
• It is recommended to clarify that Cycloferon is not an antibiotic drug and cannot overcome a bacterial infection and completely replace antibiotic therapy.
• Instructions for use of the drug states that the combined use of antibiotics with Cycloferon potentiates the mutual action of drugs.
• Doctors are categorically against the use of alcoholic beverages in the medical treatment of viral and microbial infections. As a rule, alcohol is not compatible with medicines.
• And although the instructions do not directly say this, Cycloferon is also no exception. Negative influence on the kidneys and liver, the drug can be even more pronounced when drinking alcohol. So it is better to refrain from taking alcoholic beverages during treatment with Cycloferon.

Contraindications and side effects of Cycloferon

Despite the high immunological and antiviral efficacy, Cycloferon has a number of contraindications and side effects.

• Toxicity to the fetus and the child's body is a serious contraindication for the use of Cycloferon by children under 4 years of age, and nursing mothers.
• Chronic diseases of the liver and kidneys are the basis for contraindications in the appointment of Cycloferon.
• Thyroid diseases can provoke undesirable reactions when using Cycloferon and require treatment under the supervision of an endocrinologist.
• 5% Cycloferon liniment is contraindicated for children and adolescents under 18 years of age due to the lack of clinical observations and trials.

IMPORTANT: Cycloferon can cause allergic manifestations in the form of redness, itching, rash, swelling at the injection site of the drug. People prone to allergic manifestations should take this fact into account and notify the doctor.

Cycloferon - reviews

Prevention colds- the main way to not get sick

According to numerous reviews on the use of Cycloferon, the following conclusions can be drawn.

• Cycloferon works much more effectively in the first hours of infection with a viral infection.
• Cycloferon must be prescribed by an immunologist, according to the disease, the severity of its course and age. You should also strictly adhere to the prescribed regimen for taking Cycloferon and follow it.
• It is not recommended to self-treat with antibiotics in combination with Cycloferon. Such appointments should only be made by a doctor. In addition, viruses are resistant to antibiotics, and simultaneous use with Cycloferon can hide the real picture of the disease.

Frequent colds: runny nose, sore throat, cough, fatigue and apathy often haunt us in autumn-winter period. The body reacts painfully to the lack of sun rays, fresh vegetables and fruits, physical activity.

To increase your immunity, it is not necessary to use medicinal immunomodulators, it is much easier and more pleasant to follow our advice.

Highly simple rules life: how not to get sick?

• The habit of eating varied, full and balanced will strengthen the body and immunity.
• Watch your weight and don't overeat! Increase the amount of fresh fruits, berries and vegetables in your diet. Remember, if you eat only one apple 15 minutes before the main meal, the body will absorb 200 calories less.
• Live in harmony with yourself and nature. Make plans, fantasize. Wake up and go to sleep with a smile - stable and balanced nervous system keeps pace with the immune system.
• It is possible to strengthen the immune system with the help of medicines. But, it is important to remember that the decisive word in right choice immunostimulatory drug, dosage and algorithm for its use, should remain with the immunologist. Self-medication can harm your health.

Name: Cycloferon (Cycloferon)

pharmachologic effect
Cycloferon refers to immunomodulatory and antiviral agents. The drug is a high-molecular inducer of the formation endogenous interferon. The effectiveness of the drug is due to a wide range of biological activity: anti-inflammatory, antiproliferative, antiviral, immunomodulatory, antitumor effect. Cycloferon, when introduced into the body, potentiates the formation and content in tissues and organs of high titers of beta and alpha interferons.

A particularly high content of interferons is determined in tissues and organs containing a large number of lymphoid elements: liver, spleen, lungs, intestinal mucosa. It also activates stem cells bone marrow, causing intensive formation of granulocytes. Normalizes the ratio of T-helpers and T-suppressors, promotes the activation of killer cells and T-lymphocytes. With immunodeficiencies of various origins, this causes a correction of the body's immune status. Able to penetrate the blood-brain barrier.

Cycloferon causes clinical improvement in viral infectious diseases (herpes, influenza, tick-borne encephalitis, hepatitis, cytomegalovirus infection, HIV infection, papillomatous and enterovirus infections). Due to the activation of the immune system, it has an anti-chlamydial and antimicrobial effect. It prevents the formation of tumor processes in the body due to antimetastatic and anticarcinogenic effects. It suppresses autoimmune reactions of the body, which is manifested by a decrease in the severity of pain and inflammation in systemic connective tissue diseases and rheumatic diseases.
When applied topically, Cycloferon causes an improvement in the balance of the immune system, and also has antiproliferative and anti-inflammatory effects.

After internal administration of Cycloferon at the maximum allowable dosage, the active substance is found in the maximum plasma concentration after 2-3 hours. In the future, the concentration of the drug decreases by 8 hours. A day after taking Cycloferon can be detected in the body in trace concentrations. The half-life is 4-5 hours. With the appointment of Cycloferon in the recommended dosages, no accumulation of the active substance is observed.

Indications for use
Cycloferon - tablets
herpes infection,
influenza and acute respiratory infections (acute respiratory diseases),
acute intestinal infections,
neuroinfections (including tick-borne borreliosis - Lyme disease, serous meningitis),
secondary immunodeficiency caused by chronic fungal and bacterial infections.
viral chronic hepatitis C and B,

In pediatrics - as part of complex therapy for:
herpes infection,
viral chronic and acute hepatitis C and B,
acute intestinal infections,
for the treatment and prevention of acute respiratory diseases and influenza.

For adults - as part of complex therapy for:
HIV infection in the clinical stage 2A-3B,
viral hepatitis C, A, D and B,
systemic connective tissue diseases and rheumatic diseases (systemic lupus erythematosus, rheumatoid arthritis),
neuroinfections (including tick-borne borreliosis - Lyme disease, serous meningitis, encephalitis),
cytomegalovirus or herpetic infection,
secondary immunodeficiency caused by chronic or acute fungal and bacterial infections,
chlamydial infections,
degenerative-dystrophic diseases of the joints (including deforming osteoarthritis).

In pediatrics (children over 4 years old) - as part of complex therapy for:
viral hepatitis C, A, D, GP and B,
herpes infection,
HIV infection in the clinical stage 2A-3B.

As a component of complex treatment in adults with:
herpes infection,
therapy of nonspecific vaginosis and bacterial vagititis,
treatment of balanoposthitis, specific urethritis (chlamydial, gonorrheal, trichomonas), candidal and non-specific etiology.

Mode of application
Cycloferon - tablets
Assign 1 time per day for half an hour before meals. The tablet is washed down with water, do not chew.

In case of herpetic infection for adults, Cycloferon is prescribed to receive 2-4 tablets according to the scheme: 1st, 2, 4, 6, 8, 11, 14, 17, 20 and 23rd days (basic scheme) - in total for the course of therapy - 20-40 tablets (3-6 g). Treatment begins at the time of exacerbation of the disease.

For acute respiratory infections and influenza - 2-4 tablets 1 time per day. Total for the course of therapy - 10-20 tablets (1.5-3 g). Assign at the first symptoms of the disease. In the case of a severe clinical picture, 6 tablets can be used at the first appointment. Treatment with Cycloferon is combined with painkillers, antipyretics and expectorants (if necessary and according to indications).

In viral chronic hepatitis C and B - 4 tablets per day according to the scheme: 1st, 2, 4, 6, 8, 11, 14, 17, 20 and 23rd days. Then they switch to a maintenance dose of the drug, 4 tablets 1 time in 3-5 days for 3.5 months (in case of preservation of the cytolytic and replicative activity of the infectious process). Total for the course of treatment - 100-150 tablets. The course of therapy must be repeated if the patient has viral hepatitis C or a mixed form of infection. Repeated courses of Cycloferon are prescribed 2 times: each - 1 month after the end of the previous one. Assigned in conjunction with antiviral agents and interferon.

For intestinal infections (as part of complex treatment), 2 tablets are prescribed according to the scheme: 1st, 2, 4, 6, 8th days. Further - at the reception of 2 tablets on the 11th, 14th, 17th, 20th and 23rd days. Total for the course of treatment - 20 tablets (3 g).

With neuroinfections, 4 tablets are prescribed for admission according to the scheme: 1st, 2, 4, 6, 8, 11, 14, 17, 20 and 23rd days. Then they switch to a maintenance dosage - to take 4 tablets 1 time in 5 days. The total duration of treatment is 2.5 months (100 tablets - 15 g).

In case of HIV infection in the clinical stage 2A-3B, 4 tablets are prescribed according to the scheme: 1st, 2, 4, 6, 8, 11, 14, 17, 20, 23rd days of treatment. Then they switch to a maintenance dosage: to take 4 tablets 1 time in 3-5 days. The duration of the course of treatment is 2.5 months. Total for the course of 100-150 tablets. After the end of the previous course, after 2-3 weeks, the treatment is repeated according to the same scheme.

In case of immunodeficiencies, 2 tablets are prescribed according to the scheme: 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th, 23rd days of treatment. Total for the course of therapy - 20 tablets (3 g).
In pediatrics, Cycloferon is prescribed in the following doses: for children 4-6 years old - to take 1 tablet (150 mg), at the age of 67-11 years - to take 2 tablets (300 mg), from 12 years old - to take 3 tablets (450 mg) 1 time per day. If it is necessary to repeat the course of therapy, Cycloferon is prescribed 2-3 weeks after the end of the previous course.

Viral acute hepatitis C and B: use the recommended dosage for children 2 times with an interval of 24 hours. Then appoint 3 times with an interval of 48 hours. In the future, 5 doses of Cycloferon are used after 72 hours. Depending on the age, the total for the course of therapy is 10-30 tablets.

Viral chronic hepatitis C and (or) B: Cycloferon is prescribed in the recommended dosages for children with an interval of 48 hours. Total for the course of treatment - 50-150 tablets (depending on age).

With HIV infection in the clinical stage 2A-3B, Cycloferon is prescribed to children at the recommended dosage according to the scheme: 1st, 2, 4, 6, 8, 11, 14, 17, 20 days of treatment. Then they switch to maintenance reception 1 time in 3-5 days for 5 months.

In case of herpetic infection, it is prescribed according to the scheme: 1st, 2nd, 4th, 6th, 8th, 11th, 14th days of treatment. The duration of the drug depends on the severity clinical manifestations and severity of the disease.

For acute intestinal infections, it is prescribed according to the scheme: 1st, 2nd, 4th, 6th, 8th, 11th days of treatment 1 time per day in the recommended doses for children. Total for the course of treatment 6-18 tablets.

During the epidemiological unfavorable situation for the prevention of influenza and acute respiratory diseases, Cycloferon is prescribed in the recommended doses for children according to the scheme: 1st, 2, 4, 6, 8th days, then 5 more times with an interval of 72 hours. For a course of treatment - 10-30 tablets.
For influenza and acute respiratory diseases, Cycloferon is prescribed in the recommended doses for children with an interval of 24 hours. For the course of treatment - 5-9 doses of the drug (1 time per day).

Cycloferon for parenteral use
Use the basic scheme of drug administration (1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th, 23rd, 26th, 29th days of treatment), which will depend on the type of disease. Apply intravenously or intramuscularly 1 time per day.

With viral hepatitis B, A, D, C, a single dose of Cycloferon is 250-500 mg. In total for the course of treatment - 10 injections according to the basic scheme. The total total dose is 2.5-5 g. The course is repeated after 10-14 days.

With cytomegalovirus and herpetic infections, Cycloferon is prescribed according to the basic scheme. Total for the course of treatment - 10 injections of 250 mg. The total total dose is 2.5 g. The most effective use of the drug is at the beginning of an exacerbation of the disease.

With neuroinfections, Cycloferon is prescribed according to the basic scheme. Total for the course of therapy - 12 injections of 250-500 mg. Treatment with the drug should be combined with etiotropic therapy. The total total dose is 3-6 g. If necessary, therapy can be repeated.

With HIV infection in the clinical stage 2A-3B, Cycloferon is prescribed in a single dose of 500 mg intramuscularly. In total, the course of treatment according to the basic scheme is 10 injections. The total total dose is 5 g. After the end of the basic course, maintenance treatment is prescribed 1 time in 5 days for 2.5 months. 1 month after the end of the last course, a second course of therapy is prescribed.

For chlamydial infections, Cycloferon is prescribed at a dose of 250 mg. Total for the course of treatment - 10 injections. The total total dose is 2.5 g. 10-14 days after the end of the last course, a second course of therapy is prescribed.
A combination of Cycloferon with antibacterial drugs is recommended.

In immunodeficiency states, 10 injections are prescribed per course of treatment. Apply intramuscular administration of the drug in a single dose of 250 mg according to the basic scheme. The total total dose is 2.5 g. 6-12 months after the end of the last course, a second course of therapy is prescribed.

In case of systemic diseases of the connective tissue and rheumatic diseases, the basic scheme for the administration of Cycloferon is prescribed for 5 injections (4 courses). Dose - 250 mg with an interval of 10-14 days. The need for re-appointment of Cycloferon is determined by the doctor individually.

With degenerative-dystrophic diseases musculoskeletal system prescribed according to the basic scheme of 250 mg - only 2 courses of 5 injections with an interval of 10-14 days. The need for re-appointment of Cycloferon is determined by the doctor individually.
In pediatrics: the daily dose of Cycloferon is calculated based on 6-10 mg / kg of the patient's body weight. It is used intramuscularly or intravenously 1 time per day.

In viral acute hepatitis B, A, C, GP, D and mixed forms, Cycloferon is prescribed according to the scheme: 1st, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28th day of treatment. In the case of a protracted course of infection, it is necessary to repeat the course in 10-14 days.

In viral chronic hepatitis C, B, GP, D, Cycloferon is prescribed according to the scheme: 1st, 2, 4, 6, 8, 10, 12, 14, 16, 18 days of treatment. Then - maintenance therapy 1 time in 3 days for 3 months (in case of preservation of the cytolytic and replicative activity of the infectious process).

With HIV infection, Cycloferon is prescribed according to the scheme: 1st, 2, 4, 6, 8, 10, 12, 14, 16, 18 days of treatment. Then maintenance therapy is used 1 time in 5 days for 3 months (in case of preservation of the replicative activity of the infectious process). With mixed forms of infections (HIV infection, hepatitis), chronic hepatitis C, it is possible to extend maintenance treatment for up to 6 months.

In case of herpetic infection, Cycloferon is prescribed according to the scheme: 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th, 23rd days of treatment. Therapy can be continued up to 4 weeks of maintenance dosage - a single injection every 5 days.

Cycloferon for local use
In case of herpetic infection: Cycloferon liniment is applied to the affected area with a thin layer 1 time per day for 5 days. In the case of genital herpes, daily intraurethral and (or) intravaginal instillations of 1 vial of liniment (5 ml) are carried out once a day for 10-15 days. Liniment can be combined with other local and systemic antiherpetic agents.

With candidal and nonspecific urethritis, instillations are carried out into the urethra in the amount of 1-2 vials (5-10 ml). The dose in this case depends on the level of damage to the urethra. In the case of a pathological process in the anterior part of the male urethra, the cannula of the syringe with the collected Cycloferon liniment is immersed in the external opening of the urethra, after which the opening is compressed for 1.5-3 minutes. After some time, the instillation solution is released by gravity. After half an hour, the patient should urinate, since a longer exposure to Cycloferon can cause swelling of the urethral mucosa. In case of damage to the posterior urethra and (or) seminal glands, intraurethral instillations of the drug are used through a urethral catheter in the amount of 1-2 bottles (5-10 ml) of Cycloferon liniment for 10-14 days 1 time per day every other day. Total for the course of treatment - 5-7 instillations.
For the treatment of specific urethritis, an addition in the form of specific antibacterial agents used according to standard schemes is necessary.

With candidal colpitis, bacterial vaginosis, nonspecific colpitis and (or) endocervicitis, it is possible to use Cycloferon as monotherapy or as part of complex treatment. Apply Cycloferon-liniment instillations into the vagina in the amount of 1-2 vials (5-10 ml) for 10-15 days every day. To avoid free leakage of the liniment, the entrance to the vagina must be plugged with a small sterile cotton swab for 2-3 hours. When intravaginal and intraurethral infections are combined, it is recommended to use combined instillations into the vagina and urethra in the amount of 1 vial (5 ml) for 10-15 days everyday. It is allowed to use liniment in the form of tampons impregnated with the preparation.

Cycloferon liniment can be combined with other official vaginal dosage forms in case of chronic diseases (vaginal suppositories, tablets).

Side effects
Allergic manifestations to cycloferon and other components of the drug.

Contraindications
For internal administration and parenteral administration - cirrhosis of the liver (decompensated),
allergic reactions to cycloferon and other components of the drug.

Pregnancy
Cycloferon is contraindicated for pregnant women and nursing mothers. During lactation, the liniment of cycloferon is not contraindicated.

drug interaction
The drug is fully compatible with other drugs that are prescribed for the treatment of these diseases (including chemotherapy and interferons).

Overdose
Information is absent.

Release form
Tablets Cycloferon - enteric-coated brown-golden or Brown color. Tablets are available in polymer or dark glass jars (50 pieces each) and in blisters of 10 pieces. In a cardboard box 1 or 5 blisters.

Cycloferon - solution for injection - in ampoules of 2 ml (12.5%). In the ampoule - liquid yellow color, transparent. 1 ml solution for injection contains 125 mg of the drug (in 1 ampoule - 250 mg). In a carton box 5 ampoules in contour packaging.

Cycloferon liniment 5% - yellow liquid ointment, 5 ml in a tube.

Storage conditions
Cycloferon is recommended to be stored in a dry place protected from light at a temperature of 18-20°C. Tablets and liniment are stored for no more than 2 years; solution for injection - 3 years. Short-term freezing of the injection solution is allowed (during transportation) - this does not change the medicinal and physico-chemical properties of the drug. Frozen solution for injection should only be thawed at room temperature. In the event of the formation of a precipitate or a change in the color of the solution for injection, the drug should not be used.

Compound
Tablets Cycloferon
Active ingredients: acridoneacetic acid (150 mg per tablet), N-methylglucamine (146 mg per tablet).
Inactive substances: calcium stearate, methylcellulose.

Solution for injection Cycloferon
Active ingredients: acridoneacetic acid (125 mg in 1 ml, 250 mg in 1 ampoule).
Inactive substances: water for injection, stabilizing and salt-forming additive (N-methylglucamine 192.9 mg in 2 ml).

Cycloferon liniment
Active ingredients: acridoneacetic acid in the form of N-methylglucamine salt (50 mg per 1 g of liniment).
Inactive substances: 1,2-propylene glycol up to 100% (base), catapol 0.1% (antiseptic).

Active ingredients: acridoneacetic acid, N-methylglucamine

Additionally
The use of the drug orally or as an injection in diseases of the thyroid gland should be carried out under the close supervision of an endocrinologist.

Attention!
Description of the drug Cycloferon" on this page is a simplified and supplemented version of the official instructions for use. Before purchasing or using the drug, you should consult a doctor and read the annotation approved by the manufacturer.
Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide on the appointment of the drug, as well as determine the dose and methods of its use.

Instructions for the use of cycloferon tablets, a description of the action of the drug, indications for the use of cycloferon tablets, interaction with other drugs, the use of cycloferon (tablets) during pregnancy. Instructions: ; ;

Tradename:	CYKLOFERON®
International name:	Not
Dosage form:	Enteric coated tablets 150 mg
Indications for use:
ATS classification:	L Antineoplastic and immunomodulatory agents L03 Immunostimulants L03A Immunostimulants L03A X Other immunostimulants
Pharm. Group:	Other immunostimulants. ATC code L03AX
Storage conditions:	Store in a dry, dark place at a temperature of 10 to 25 ºС. Keep out of the reach of children!
Shelf life:	2 years. Do not use after the expiry date stated on the packaging.
Terms of sale:	On prescription
Description:	Tablets, enteric-coated, yellow, with a biconvex surface.

Instruction content:

Composition of cycloferon in tablets

One tablet contains

Bir tabletkanyn kuramynda:

The active substance of cycloferon

meglumine acridone acetate in terms of acridoneacetic acid 150 mg, obtained according to the following prescription: acridoneacetic acid 150 mg, N-methylglucamine (meglumine) 146 mg

150 mg meglumine acridone acetates, acridonsirke kyshkylyna shakanda kelesi zhazba boyinsha alyngan: 150 mg acridonsirke kyshkyly, 146 mg N-methylglucamine (meglumine)

Auxiliary substances in cycloferon

povidone, calcium stearate, hypromellose, polysorbate 80, enteric coating: methacrylic acid and ethyl acrylate copolymer, propylene glycol

povidone, calcium stearates, hypromellose, polysorbate 80

Indications for the use of cycloferon tablets

In adults as part of complex therapy

• herpetic infection

• secondary immunodeficiencies associated with chronic bacterial and fungal infections

In children from 6 years of age as part of complex therapy

• influenza and acute respiratory infections

• herpetic infection

• chronic viral hepatitis B and C

• acute intestinal infections (shigellosis, yersiniosis)

In children from 6 years of age for prevention:

• influenza and acute respiratory infections

Eresekterde keshendі em kuramynda

• herpestic zhұқpa

• sozylmaly bacteriallyk zhane zendik zhұқpalarmen astaskan saldarly immuntapshylygy

Balalarda 6 zhastan bastap keshendі em құramynda

• tumau zhane zhedel respirators aurular

• herpestic zhұқpa

• cozymals viruses B zhane C hepatitisTER

• ishektin zhedel zhұқpalary (shigellosis, yersiniosis)

Balalarda 6 zhastan aldyn alu ushin:

• tumau zhane zhedel respirators aurular

Contraindications of cycloferon in tablets

• hypersensitivity to the components of the drug

• pregnancy and lactation

• children's age up to 6 years

• severe liver disease

• liver failure

• drug componentterine jogary sezimtaldyk

• zhuktilik zhane lactation kezen

• 6 zhaska deyingі balalarga

• bauyrdyn auyr aurulary

• bauyr zhetkіlіksіzdіgі

Side effects of cycloferon tablets

Rarely:

• allergic reactions in the form of skin rashes

• exacerbation of chronic gastritis

• exacerbation of neurodermatitis

• exacerbation of chronic cholecystitis

Sirek:

• terі bөrtpesі turіndegі allergic reactions

• sozylmaly gastritis өrshuі

• neurodermatitis orshui

• sozylmaly cholecystitis orshui

Special instructions for use

In case of thyroid diseases, it is necessary to consult an endocrinologist to exclude the possibility of autoimmune disorders. Features of the effect of the drug on the ability to drive vehicles or potentially dangerous machinery. Cycloferon does not affect the ability to drive vehicles or potentially dangerous mechanisms.

Kalkansha without aurulary kezinde autoimmunity buzylulardyn lady mүmkіndіgin anyқtau ushіn endocrinologist-darіgermen kenesu kazhet.

Darіlіk zattardyn kоlik құraldaryn nemese әleutti қауіпті mechanism derdi baskaru kabіletіne аser etu erekshelіkterі

Cycloferon kөlіk құraldaryn nemese әleuttі қauіptі mechanism derdi baskaru kabіletіne aser etpeidі.

Dosage and method of application

Inside once a day 30 minutes before meals, without chewing, drinking ½ glass of water, at the rate of 10 mg / kg of body weight, in age dosages: for children 6 years old: 150 mg (1 tablet) per dose, the maximum daily dose is 150 mg (1 tablet); children 7–11 years old: 300–450 mg (2–3 tablets) per dose, maximum daily dose 450 mg (3 tablets); adults and children over 12 years old: 450-600 mg (3-4 tablets) per dose, maximum daily dose of 900 mg (6 tablets). It is advisable to repeat the course 2-3 weeks after the end of the first course.

In adults:

1. In the treatment of influenza and acute respiratory diseases, the drug is taken at 600 mg (4 tablets) on the 1st, 2nd, 4th, 6th, 8th day. Treatment should be started at the first symptoms of the disease. In severe cases of influenza, 600-900 mg (4-6 tablets) are taken on the first day, then at the age dosage. If necessary, symptomatic therapy is additionally carried out (antipyretic, analgesic, expectorant drugs). The course of treatment (20-30 tablets).

2. For herpetic infection, the drug is taken at 300-600 mg

4. In chronic viral hepatitis B and C, the drug is taken according to

600 mg (4 tablets) for admission on days 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 of treatment and then according to the maintenance regimen 1 time in 3-5 days during

2.5 months while maintaining the replicative and cytolytic activity of the pathological process. The course of treatment is 100-150 tablets. In chronic hepatitis C and mixed forms of hepatitis, the course of treatment must be repeated one or two more times a month after the end of the previous one. A combination with interferons and antiviral drugs is recommended.

In children from 6 years of age:

1. For influenza and acute respiratory diseases, as well as for emergency non-specific prevention of influenza and acute respiratory diseases (in direct contact with patients with influenza or acute respiratory infections of other etiologies, during an influenza epidemic), the drug is taken in age doses for 1, 2, 4, 6 , 8, 11, 14, 17, 20, 23 days. The course of treatment is from 5 to 10 doses, depending on the severity of the condition and the severity of clinical symptoms.

Ishka tәuligina bir rt kabyldagaa deien 30 minutes Bұryn, shainamai ½ cup of Sumen I was, Salmanyna 10 mg/kg Eseppen, Zhasyna Karay Dota Kabyldaida: 6 Zhastai Balalarg 1 tablet); 7–11 zhastagy balalarga: kabyldauga 300–450 mg (2–3 tablets), en zhogary tauliktik dose 450 mg (3 tablets); eresekter men12zhastan askan balalarga: kabyldauga 450–600 mg (3–4 tablets), en zhogary tauliktik dose 900 mg (6 tablets). Kaytalau kursyn algashky courses ayaktalgannan keyin 2–3 aptadan son zhurgizu maqsatka sai.

Eresekterde:

1. Tumau men zhedel respiratorlyk aurulardy emdeude preparations 600 mg-dan (4 tablets) 1, 2, 4, 6, 8-shі tәulіkte қabyldaydy. Emdeudi aurudyn algashky symptomdarynda bastau kerek. Tumaudyn auyr agymynda algashky kүnі 600-900 mg (4-6 tablets) It seems that the Bolganda qosymsha symptomatically em zhүrіzedі (ystyқ tүsіretіn, ауyrudy basatyn, қақырiқ tүsіrіtіn dаriler). Emdeu courses (20–30 tablets).

2. Herpestic zhұқpada preparations 300-600 mg-dan

4. Sozylmaly virustyk In Zhane With hepatitis inde preparations

600 mg-dan (4 tablets) emdeudin 1, 2, 4, 6, 8, 11, 14, 17, 20

2.5 ai ishinde 3-5 kүnde 1 Emdeu courses 100-150 tablets. Sozylmaly With hepatitisinde zhane hepatitistin mixed-turlerinde emdeu kursyn aldyngy em ayaktalgannan keyin bir aidan keyin mindetti tүrde tagy bir ekі ret kaitalaydy. Interferonmen zhane viruska karsy drug tarmen biriktir ұsynylady.

Tauliktik dosed kabyldagan kezde kan plasmasyndagy en zhogary concentration son 2-3 sagattan keyin zhetedi, 8-shі sagatka karay concentrations birtindep tömendeydi, al 24 saғattan keyіn Cycloferon- ny. Preparatyn zhartylai shygarylu kezeny 4-5 sagatty kuraydy, sondyktan ony ұsynylgan dozada paydalan organismde zhinaқtaluyna zhagday zhasamaydy.

Pharmacodynamics

Cycloferon is a low molecular weight inducer of early interferon, which determines the spectrum of its biological action: antiviral, immunomodulatory, anti-inflammatory, etc., causing the production of alpha and gamma interferon within a day from the moment of administration. Stimulation of interferon synthesis by the drug occurs at the level of transcription of the corresponding gene and is not due to its effect on post-transcriptional processes, such as an increase in the rate of translation, stabilization of IFNα mRNA, or the mRNA-ribosome complex, as well as the release of previously synthesized interferon.

The immunoregulatory properties of the drug are largely mediated through the interferon system, namely through the activation of alpha and gamma interferon. With an increase in its production, Cycloferon helps to restore the T-cell link of immunity: it normalizes the levels of subpopulations of CD3+ (T-lymphocytes), CD4+ (T-helpers), as well as the number of CD16+ (NK cells), CD8+, CD72+ and immunoregulatory index. The direct effect of the drug in viral infections is to disrupt virus replication, block the incorporation of viral DNA or RNA into capsids, increase the number of defective viral particles, and reduce virus-induced protein synthesis in cells.

Cycloferon Bastaps Interferonny Tөmenmoleklarly Inductors Bolyp Tabylady, Bul Biologili әserinіn Spectrine: Engizіlgen sәtap tәulik waist alpha gamma-b-byanda қAba, immunmodulda, immunmodulda. anyқtaydy. Препаратпен интерферон синтезін ынталандыру сәйкес геннің транскрипциясы деңгейінде жүреді және трансляция жылдамдығының жоғарылауы, мРНҚ IFNα немесе мРНҚ – рибосома кешенінің тұрақтануы, сондай - ақ бұрын синтезделген интерферонның шығарылуы секілді оның посттранскрипциялық үдерістерге әсеріне байланысты емес.

Preparation of immunoregulatory kasietteri negizinen interferondar zhүyesі arkyly, dalirek aitsak alpha-zhane gamma-interferondy belsendіlendіru arkyly zhuredi. Циклоферон оның өндірілуі жоғарылағанда иммунитеттің Т-жасушалы тізбегін қалпына келтіруге ықпал етеді: СD3+ (Т-лимфоциттер), СD4+ (Т-хелперлер) субпопуляциясы деңгейін, сондай - ақ СD16+ (NK-жасушалар), CD8+, CD72+ мөлшерін және иммунорегуляторлық индексті қалпына келтіреді.

Preparatyn virusta zhұқpalard tikels әseri virus replicationsyn bұzuғa, virustyқ DNҚ nemese RNҚ - nyn capsidterge incorporation son bogeuge, ақаули virus bөlshekterinіn mөlsherіnіn artuyn, zhasushalardaғy virusinduktsiyalanіnғy synthesis.

Packaging and release form

Enteric-coated tablets, 150 mg. 10 tablets in a blister pack made of PVC film and aluminum foil. 1 or 5 blister packs, together with instructions for medical use in the state and Russian languages, are placed in a pack of cardboard box.

Ishekte eritin kabykpen kaptalgan tabletkalar 150 mg-den. Polyvinylchloride ulbirden zhane aluminum foildan zhasalgan pishindі yashhykty kaptamada 10 tabletdan. 1 nemese 5 pіshіndі ұyashyқty қaptamadan medicinada қoldanyluy zhөnіndegі memlekettіk zhane orys tіlderіndegі nұsқaulyқpen bіrge қoraptyқ cardboardnan zhasalғan pәshkege salynғan.

Preparation: CYKLOFERON ®
Active ingredient: non appropriated
ATX code: L03AX
KFG: Antiviral and immunomodulatory drug. Interferon synthesis inducer
ICD-10 codes (indications): A08, A56.0, A56.1, A60, A69.2, A87, B00, B02, B15, B16, B17.1, B18.1, B18.2, B24, B25, J06.9, J10, M05, M15, M32
CFU code: 09.01.05.02
Reg. number: Р №001049/03
Date of registration: 28.08.07
The owner of the reg. acc.: POLYSAN NTFF LLC (Russia)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

Enteric coated tablets yellow, biconvex.

Excipients: potato starch, calcium stearate, copolymer of methacrylic acid and ethyl acrylate, 1,2-propylene glycol.

10 pieces. - cellular contour packings (1) - packs of cardboard.
10 pieces. - cellular contour packings (5) - packs of cardboard.

Solution for intravenous and intramuscular administration transparent, yellow.

Excipients: water d / i.

2 ml - ampoules (5) - blister packs (1) - cardboard packs.

CYCLOFERON INSTRUCTION FOR A SPECIALIST.
The description of the drug cycloferon is approved by the manufacturer.

PHARMACHOLOGIC EFFECT

Immunomodulator. Meglumine acridonacetate is a low molecular weight interferon inducer, which determines wide range its biological activity (antiviral, immunomodulatory, anti-inflammatory). The interferonogenic activity of the drug after oral administration persists for 3 days.

The main cells-producers of interferon after the administration of the drug are macrophages, T- and B-lymphocytes. The drug induces high titers of interferon in organs and tissues containing lymphoid elements (spleen, liver, lungs), activates bone marrow stem cells, stimulating the formation of granulocytes. Cycloferon ® activates T-lymphocytes and natural killer cells, normalizes the balance between subpopulations of T-helpers and T-suppressors. Enhances the activity? -interferons.

It has a direct antiviral effect, suppressing the reproduction of the virus in the early stages (1-5 days) of the infectious process, reducing the infectivity of viral progeny, leading to the formation of defective viral particles. Increases the body's nonspecific resistance against viral and bacterial infections.

Cycloferon ® is effective against tick-borne encephalitis, influenza, hepatitis, herpes, cytomegalovirus, human immunodeficiency virus, papillomavirus and other viruses. In acute viral hepatitis, Cycloferon ® prevents the transition of diseases into a chronic form. At the stage of primary manifestations of HIV infection, it contributes to the stabilization of immunity indicators.

The high efficiency of the drug in the complex therapy of acute and chronic bacterial infections (neuroinfections, chlamydia, bronchitis, pneumonia, postoperative complications, urogenital infections, peptic ulcer) as a component of immunotherapy has been established. Meglumine acridonacetate is highly effective in rheumatic and systemic diseases of the connective tissue, suppressing autoimmune reactions and providing anti-inflammatory and analgesic effects.

PHARMACOKINETICS

Tablets

After taking the drug orally at the maximum allowable dose, Cmax in blood plasma is reached after 2-3 hours, the concentration gradually decreases by 8 hours, after 24 hours the active substance is detected in trace amounts.

T 1/2 is 4-5 hours. When using Cycloferon in recommended doses, there are no conditions for its accumulation in the body.

Injection

After taking the drug Cycloferon inside at the maximum allowable dose, Cmax in blood plasma is reached after 1-2 hours. After 24 hours, the active substance is detected in trace amounts.

Penetrates through the BBB.

T 1/2 is 4-5 hours. With prolonged use, cumulation in the body is not observed.

CYKLOFERON - INDICATIONS

For oral administration

adults:

herpetic infection;

Influenza and acute respiratory diseases;

Acute intestinal infections;

Neuroinfections, including serous meningitis, tick-borne borreliosis (Lyme disease);

Secondary immunodeficiencies associated with chronic bacterial and fungal infections.

As part of complex therapy for children over 4 years old:

herpetic infection;

Prevention and treatment of influenza and acute respiratory diseases;

Chronic viral hepatitis B and C;

Acute intestinal infections;

HIV infection (stage 2A-2B).

For parenteral use

As part of complex therapy for adults:

HIV infection (stages 2A-2B);

Neuroinfections: serous meningitis and encephalitis, tick-borne borreliosis (Lyme disease);

herpetic infection;

Cytomegalovirus infection;

Secondary immunodeficiencies associated with acute and chronic bacterial and fungal infections;

chlamydial infections;

Rheumatic and systemic connective tissue diseases (rheumatoid arthritis, systemic lupus erythematosus);

Degenerative-dystrophic diseases of the joints (including deforming osteoarthritis).

As part of complex therapy for children:

Viral hepatitis A, B, C, D;

herpetic infection;

HIV infection (stages 2A-2B).

DOSING REGIME OF CYKLOFERON

inside

Cycloferon ® in the form of tablets is taken 1 time / day 30 minutes before meals, without chewing.

Adults at herpetic infection the drug is prescribed for 4 tab. for admission on 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days. The course of treatment - 40 tab. Treatment is most effective when the first symptoms of the disease appear.

At treatment of influenza and acute respiratory diseases appoint 4 tab. for reception on 1, 2, 4, 6, 8 days. The course of treatment - 20 tab. Treatment should be started at the first symptoms of infection. At severe course of the disease at the first reception take 6 tab. If necessary, symptomatic therapy is additionally carried out (antipyretic, analgesic, expectorant drugs).

At chronic viral hepatitis B and C the drug is taken in 4 tab. at the reception for 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days of treatment and then according to the maintenance regimen, 4 tab. for admission 1 time in 3 days for 6 months while maintaining replicative and cytolytic activity up to 12 months. A combination with interferons and antiviral drugs is recommended.

AT complex therapy of intestinal infections apply 2 tab. for reception on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th and 23rd days. The course of treatment - 20 tab.

At neuroinfections appoint 4 tab. for admission on 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days and then according to the maintenance scheme, 4 tab. at the reception 1 time in 3 days for 2.5 months. The course of treatment - 140 tab.

At HIV infections (stages 2A-2B) the drug is prescribed for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days, 4 tab. at the reception and then carry out maintenance treatment of 4 tab. 1 time in 3 days for 2.5 months. The course of treatment - 140 tab. A second course is carried out after 2-3 weeks. after the end of the previous 2-3 times.

At immunodeficiency states associated with chronic bacterial and fungal infections appoint 4 tab. in the first 5 doses for 1, 2, 4, 6, 8 days and 2 tab. in the next 5 doses for 11, 14, 17, 20, 23 days. The course of treatment - 30 tab.

children Cycloferon ® is prescribed according to the following basic scheme: aged 4-6 years- 150 mg (1 tab.), aged 7-11 years- 300 mg (2 tab.), over 12 years old- 450 mg (3 tab.) per reception 1 time / day. It is advisable to repeat the course in 2-3 weeks. after completing the first course.

At herpetic infection take on 1, 2, 4, 6, 8, 11, 14 days of treatment. The course of treatment may vary depending on the severity of the condition and the severity of clinical symptoms.

At flu andacute respiratory viral infections the drug is prescribed in age doses for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days and then 1 time in 3 days. The course of treatment is from 5 to 15 doses, depending on the severity of the condition and the severity of the symptoms.

As a means of emergency non-specific prevention of acute respiratory diseases and influenza during a period of increased incidence the drug is prescribed in the indicated age doses for 1, 2, 4, 6, 8 days, then 5 more times with an interval of 72 hours (3 days).

At chronic forms hepatitis B and/or C the drug is prescribed in the indicated doses for 1, 2, 4, 6, 8, 11, 14 days and then 1 time in 3 days for 6 months while maintaining replicative and cytolytic activity up to 12 months. A combination with interferons and antiviral drugs is recommended.

At acute intestinal infections the drug is prescribed for 1, 2, 4, 6, 8, 11 days of treatment 1 time / day. The course of treatment - 6-18 tab.

At HIV infections (stages 2A-2B) the drug is taken according to the basic scheme for 1, 2, 4, 6, 8, 11, 14, 17, 20 days of therapy, then 1 time in 3 days for 5 months.

Parenteral application

Adults Cycloferon ® is administered intramuscularly or intravenously 1 time per day according to the basic scheme: every other day. The duration of treatment depends on the disease.

At herpetic and cytomegalovirus infections the drug is prescribed according to the basic scheme - 10 injections of 250 mg. The total dose is 2.5 g. Treatment is most effective at the beginning of an exacerbation of the disease.

At neuroinfections the drug is administered according to the basic scheme. The course of treatment - 12 injections of 250-500 mg in combination with etiotropic therapy. The total dose is 3-6 g. Repeated courses are carried out as needed.

At chlamydial infection treatment is carried out according to the basic scheme. The course of treatment is 10 injections of 250 mg. The total dose is 2.5 g. The second course is in 10-14 days. It is advisable to combine Cycloferon ® with antibiotics.

At acuteviral hepatitisA, B, C, Dand mixed forms the drug is administered according to the basic scheme of 10 injections of 500 mg. The total dose is 5 g. In case of a protracted course, a second course is carried out after 10-14 days.

At chronic viral hepatitis B, C, D and mixed forms the drug is administered according to the basic scheme of 10 injections of 500 mg, then according to the maintenance scheme 3 times a week. within 3 months as part of complex therapy. Recommended in combination with interferons and chemotherapy. The course is repeated in 10-14 days.

At HIV infection (stage 2A-2B) the drug is prescribed according to the basic scheme of 10 injections of 500 mg each, and then according to the maintenance regimen once every three days for 2.5 months. The course is repeated after 10 days.

At immunodeficiency states the course of treatment consists of 10 intramuscular injections according to the basic scheme in a single dose of 250 mg. The total dose is 2.5 g. The second course is carried out after 6-12 months.

At rheumatic and systemic connective tissue diseases prescribe 4 courses of 5 injections according to the basic scheme, 250 mg each with a break of 10-14 days. The doctor determines the need for a second course individually.

At degenerative-dystrophic diseases of the joints prescribe 2 courses of 5 injections of 250 mg with a break of 10-14 days according to the basic scheme. The doctor determines the need for a second course individually.

children Cycloferon ® is prescribed intramuscularly or intravenously 1 time per day. The daily therapeutic dose is 6-10 mg/kg of body weight.

At acute viral hepatitis A, B, C, D and mixed forms spend 15 injections of the drug according to the basic scheme. With a protracted course of infection, the course is repeated after 10-14 days.

At chronic viral hepatitis B, C, D the drug is administered according to the basic scheme of 10 injections and then according to the maintenance scheme 3 times a week for 3 months as part of complex therapy. Use in combination with interferons and chemotherapy is recommended.

At HIV infections (stages 2A-2B) a course of 10 injections is prescribed according to the basic scheme and then according to the maintenance scheme 1 time in 3 days for 3 months. A second course is carried out after 10 days.

At herpetic infection conduct a course of 10 injections according to the basic scheme. While maintaining the replicative activity of the virus, the course of treatment is continued according to the maintenance scheme with the introduction of the drug 1 time in 3 days for 4 weeks.

CYKLOFERON - SIDE EFFECTS

Maybe: allergic reactions.

CONTRAINDICATIONS

Cirrhosis of the liver in the stage of decompensation;

Children's age up to 4 years;

Pregnancy;

lactation period (breastfeeding);

Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

The drug is contraindicated for use during pregnancy and lactation (breastfeeding).

SPECIAL INSTRUCTIONS

In diseases of the thyroid gland, the use of Cycloferon ® should be carried out under the supervision of an endocrinologist.

In the treatment of influenza and SARS, in addition to therapy with Cyclofern ®, symptomatic therapy should be carried out.

Influence on the ability to drive vehicles and control mechanisms

Cycloferon ® does not affect the ability to drive vehicles.

OVERDOSE

To date, no cases of drug overdose have been reported.

DRUG INTERACTIONS

Cycloferon ® is compatible with all drugs used in the treatment of these diseases (including interferons and chemotherapy drugs).

Cycloferon ® enhances the action of interferons and nucleoside analogues.

When used together, Cycloferon ® reduces the side effects of chemotherapy and interferon therapy.

TERMS AND CONDITIONS OF DISCOUNT FROM PHARMACIES

The drug is dispensed by prescription.

TERMS AND CONDITIONS OF STORAGE

List B. Enteric-coated tablets should be stored in a dry, dark place at a temperature of 10° to 25°C. Shelf life - 2 years.

Solution for injection should be stored in a dry, dark place at a temperature of 0° to 25°C. Freezing the solution for injection during transportation (at a negative temperature) does not lead to a change in properties. Thawed at room temperature, the drug retains its biological and physico-chemical properties. If the color of the solution changes and a precipitate forms, the use of the drug is unacceptable. Shelf life - 3 years.

Cycloferon for children is a very good drug that has shown its effectiveness in incessant colds, exacerbation of chronic respiratory diseases. Many people know that a weak immune system is to blame for their occurrence.

Parents who faced the above problems in a child definitely resorted to the use of immune system correctors in therapy and for the prevention. Cycloferon is just an immunocorrector, it is worth talking about this drug in a little more detail.

Is this a good medicine? Will he help the child? What side effect can this medication have? When can you start taking the medication? The answers to these questions are interesting. caring mothers and dads, grandparents.

Desire to learn more about something medicine only welcome. Conscious treatment is always supported by doctors. However, despite the information provided about the medication, it must be remembered that only an immunologist can correctly prescribe the dosage, treatment regimen after examining the child and conducting a series of examinations.

Only in this case, Cycloferon will have a positive effect in strengthening the child's immunity, and the risks of developing side effects will be reduced to zero.

It must be remembered that no matter what form of Cycloferon is prescribed by a pediatrician (tablets, gel-ointment, injections or syrup for children), medications cannot be taken without consultation and recommendation of an immunologist.

And this is not because this medication is very dangerous, but because, like any medicine, it has some contraindications. An examination by an immunologist is necessary so that the doctor understands:

• whether it is advisable to give the drug to a child;
• whether the drug can change the condition of a small patient;
• whether the drug will give the expected effect.

In addition, only an immunologist will be able to calculate the scheme by which a particular child will be treated. The dose and scheme are selected individually. Only the doctor decides whether to drink pills or add another course of Cycloferon injections.

What does Cycloferon consist of?

The main active ingredient of the drug is acridonacetic acid. The preparation includes auxiliary components and formative substances, but it is acridonacetic acid that corrects the immune system, stimulating the production of a special protein - interferon. Thanks to the acid, protein is produced in certain areas:

• small intestine;
• spleen;
• liver;
• lungs.

The question may reasonably arise why Viferon is not an analogue of Cycloferon. The answer is simple: Cycloferon is not a product of bioengineering and does not include foreign proteins.

Therefore, Cycloferon does not give specific side effects, such as:

• diarrhea;
• flu condition;
• depression.

But this does not mean that Cycloferon does not have any side effects. What are interferons? How are they produced by our body? Acridoneacetic acid promotes the production of interferons, which are responsible for the triple action of the drug:

• fight against viruses;
• fighting inflammation;
• modulation of the immune system.

Alpha and p-interferons give antiviral action. But gamma-interferon normalizes the immune system in a child.

It is the last interferon that is fighting the exacerbation of diseases of the pulmonary system and bronchi, which arise due to reproduction. harmful bacteria and viruses. And alpha- and p-interferons fight back against influenza viruses and other viruses that give the initial symptoms of diseases (runny nose, cough, sore throat).

When is a medication used, how does it fight chronic ailments?

Of course, we all know that viruses that enter our body can provoke not only the development of colds, but also such terrible diseases as HIV, herpes, and viral hepatitis. All these diseases can be overcome by our alpha and p-interferons. Especially if they join the fight at the very beginning of the disease. That is why doctors often prescribe medication in the form of ointments, tablets or injections to treat herpes.

The drug is widely used to treat the initial manifestations of AIDS and viral hepatitis and shows positive results. It seems that this is a miracle drug, a panacea for all colds and viral infections. I drank a course of immunocorrector - and the problems disappeared by themselves. But all is not as rosy as one would like to see.

Let's turn to the instructions, learn how to use the medication according to the rules. And also we will study all forms of Cycloferon and their application.

So, how to take Cycloferon for children: instructions for use indicate that the tablet contains 150 mg of the active ingredient. The tablet is coated with a special shell. The shell prevents the combination of acridoneacetic acid with hydrochloric acid in the stomach and does not change the composition of the former. It should be remembered that the tablet should not be chewed or broken.

Another important point: the drug in tablets is taken on an empty stomach, 30 minutes before a meal. it important condition which cannot be ignored.

It is important to follow the rules on how to take Cycloferon, then the active substance will enter the small intestine free from food and begin to work for the benefit of the body with 100% efficiency. If the small intestine is ulcerated, damaged, if metabolic processes are disturbed in it, then Cycloferon will be powerless. It is also important that the drug has a shelf life of 2 years.

Dosage and use of injections

Cycloferon tablets are very often used for both treatment and prevention. viral diseases(in particular, for the prevention of influenza). The scheme is determined by the doctor, since it is different in each case. The dosage depends on the age of the child or adult, on body weight and on the presence of chronic diseases. If you follow all the recommendations of the attending doctor, then the drug will provide real help to the body, and the therapy will not cause negative consequences.

In addition to tablets, Cycloferon is available in 2 ml ampoules for intramuscular and intravenous injections. It should immediately be said that in case of respiratory diseases, injections are practically not prescribed. Injections are prescribed with a sharp decrease in immunity, with chronic bronchitis and sluggish pneumonia in combination with other medicines. Often, hepatitis and complex forms of herpes are treated with injections. Injections have a very good effect in the treatment of meningitis, encephalitis. In many diseases of the brain, Cycloferon injections are prescribed.

In addition, injections of the drug are prescribed in the complex therapy of diseases such as:

• AIDS;
• rheumatoid arthritis;
• arthrosis with deformity;
• lupus erythematosus.

Injections are also prescribed by a doctor, and the scheme is determined individually. Injections very rarely do not have a positive effect. According to statistics, Cycloferon injections give the best effect and are well tolerated by patients. However, it is often possible to encounter the fact that after treatment a relapse of the disease occurs. This usually happens if violations of the drug regimen were made when the patient did not complete the full course of Cycloferon injections.

It is absolutely impossible to cancel the drug on your own. It is because of this that the problems that quickly disappeared will soon return again, and even in a more severe form.

It should be understood that the medication in injections can only be used as prescribed by the doctor. In addition, the doctor must monitor the patient's condition, conduct an examination. Control is required, since the introduction of the drug can cause an unpredictable reaction of the body. And although Cycloferon has practically no contraindications, it is necessary to treat the state of health of a child or an adult with all responsibility.

The use of ointments and contraindications

There are no such dosage forms of Cycloferon as candles, sprays, etc. You may encounter fakes. Another form of release of Cycloferon is 5% liniment, i.e. ointment. In the form of a 5% ointment, the drug is used for external manifestations of herpes. Sometimes the ointment is prescribed for the treatment of gonorrhea, trichomoniasis and other diseases of the reproductive system in women. The dose of the medication and the scheme for using the ointment are also prescribed by the attending physician. If a child or an adult has a tendency to allergies, then Cycloferon (ointment and injections) should be used with extreme caution. In addition, children under 4 years of age should not use Cycloferon. You can not use the medicine during the bearing of the child and during lactation. If the patient has problems with the thyroid gland, then the drug can be used only under the supervision of an endocrinologist.

When prescribing Cycloferon, children should be very careful. It must be remembered that the dosage and regimen of the drug should be prescribed by a pediatric immunologist. Make sure that children do not chew the tablet when taking the medicine, but swallow it whole. In addition, we must not forget that the tablets should be taken 30 minutes before meals.

Cycloferon injections prescribed for children should be done only in a hospital setting. It is important to understand the fact that the drug is not an antibiotic, it cannot replace an antibacterial drug in the treatment of bronchitis, influenza, pneumonia and other viral infections. This is an immunity corrector, and it only helps the body fight the disease, and antibiotics should disinfect. Cycloferon - very good drug and is often prescribed by doctors as a complex therapy, however, it should be remembered that only an immunologist can prescribe the drug. Self-administration of medication can cause extremely undesirable consequences.